skip to Main Content
Neliti website       This is an archived version of the old Neliti website. For the new website, please visit www.neliti.com

Vertical transmission of dengue virus in Aedes aegypti collected in Surabaya, Indonesia, during 2008-2011

Dengue fever is a mosquito-borne disease of major global public health concern. Since 2004, Indonesia has witnessed
the largest incidence of dengue fever in Southeast Asia. Surabaya, the second largest city in Indonesia and
the capital of the East Java province, has had an annual incidence of approximately 2,000–3,000 dengue cases
and 10 associated deaths, over the past 10 years. Infective female Aedes mosquitoes can transmit 4 different dengue viruses (designated DENV 1–4) to humans. This horizontal transmission between mosquito vectors and human hosts is the primary mechanism for the maintenance of the virus in urban areas. Vertical transmission via the transovarial route in female Aedes mosquitoes also occurs in nature. This mechanism is particularly important for maintenance of
the virus, because mosquito eggs are capable of surviving in the environment even under adverse conditions for long periods. Vertical transmission in Aedes aegypti L., the principal vector for DENV1–4, has been proven experimentally and in the field. However, the extent to which vertical transmission affects the percentage of infected Ae. aegypti population during the dry and rainy seasons is unclear. In the present study, we examined the field-collected adult males, females, and larvae, as well as adults that had emerged from the field-collected larvae, for the presence of viral RNA; the minimum infection rates (MIRs) of the viruses were determined and comparisons made between the findings obtained in the dry and rainy seasons in Surabaya.

Download Full Text

Leave a Reply

Back To Top